West nile virus RNA not detected in urine of 40 people tested 6 years after acute West Nile virus disease.

نویسندگان

  • Katherine B Gibney
  • Robert S Lanciotti
  • James J Sejvar
  • C Thomas Nugent
  • Jeffrey M Linnen
  • Mark J Delorey
  • Jennifer A Lehman
  • Erin N Boswell
  • J Erin Staples
  • Marc Fischer
چکیده

West Nile virus (WNV) causes an acute infection that is usually cleared by an effective immune response after several days of viremia. However, a recent study detected WNV RNA in the urine of 5 of 25 persons (20%) tested several years after their initial acute WNV disease. We evaluated an established cohort of 40 persons >6 years after initial infection with WNV. Urine collected from all participants tested negative for WNV RNA by reverse-transcription polymerase chain reaction and transcription-mediated amplification. Prospective studies are needed to determine if and for how long WNV persists in urine following WNV disease.

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عنوان ژورنال:
  • The Journal of infectious diseases

دوره 203 3  شماره 

صفحات  -

تاریخ انتشار 2011